BTK suppresses myeloma cellular senescence through activating AKT/P27/Rb signaling

We previously explored the role of BTK in maintaining multiple myeloma stem cells (MMSCs) self-renewal and drug-resistance. Here we investigated the elevation of BTK suppressing MM cellular senescence, a state of irreversible cellular growth arrest. We firstly discovered that an increased expression...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:Oncotarget
Main Authors: Gu, Chunyan, Peng, Hailin, Lu, Yue, Yang, Hongbao, Tian, Zhidan, Yin, Gang, Zhang, Wen, Lu, Sicheng, Zhang, Yi, Yang, Ye
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2017
Teme:
Research Paper
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5593608/
https://ncbi.nlm.nih.gov/pubmed/28915637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18096
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki