Treatment with the WNT5A-mimicking peptide Foxy-5 effectively reduces the metastatic spread of WNT5A-low prostate cancer cells in an orthotopic mouse model

Prostate cancer patients with high WNT5A expression in their tumors have been shown to have more favorable prognosis than those with low WNT5A expression. This suggests that reconstitution of Wnt5a in low WNT5A-expressing tumors might be an attractive therapeutic approach. To explore this idea, we h...

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Bibliografske podrobnosti
izdano v:PLoS One
Main Authors: Canesin, Giacomo, Evans-Axelsson, Susan, Hellsten, Rebecka, Krzyzanowska, Agnieszka, Prasad, Chandra P., Bjartell, Anders, Andersson, Tommy
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science 2017
Teme:
Research Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590932/
https://ncbi.nlm.nih.gov/pubmed/28886116
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0184418
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