The loss-of-function disease-mutation G301R in the Na(+)/K(+)-ATPase α(2) isoform decreases lesion volume and improves functional outcome after acute spinal cord injury in mice

BACKGROUND: The Na(+)/K(+)-ATPases are transmembrane ion pumps important for maintenance of ion gradients across the plasma membrane that serve to support multiple cellular functions, such as membrane potentials, regulation of cellular volume and pH, and co-transport of signaling transmitters in all...

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Veröffentlicht in:BMC Neurosci
Hauptverfasser: Ellman, Ditte Gry, Isaksen, Toke Jost, Lund, Minna Christiansen, Dursun, Safinaz, Wirenfeldt, Martin, Jørgensen, Louise Helskov, Lykke-Hartmann, Karin, Lambertsen, Kate Lykke
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5590116/
https://ncbi.nlm.nih.gov/pubmed/28886701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12868-017-0385-9
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