MicroRNA-449a deficiency promotes colon carcinogenesis

MicroRNAs have broad roles in tumorigenesis and cell differentiation through regulation of target genes. Notch signaling also controls cell differentiation and tumorigenesis. However, the mechanisms through which Notch mediates microRNA expression are still unclear. In this study, we aimed to identi...

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Udgivet i:Sci Rep
Main Authors: Niki, Masanori, Nakajima, Kohei, Ishikawa, Daichi, Nishida, Jun, Ishifune, Chieko, Tsukumo, Shin-ichi, Shimada, Mitsuo, Nagahiro, Shinji, Mitamura, Yoshinori, Yasutomo, Koji
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587792/
https://ncbi.nlm.nih.gov/pubmed/28878284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10500-0
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