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MicroRNA-449a deficiency promotes colon carcinogenesis

MicroRNAs have broad roles in tumorigenesis and cell differentiation through regulation of target genes. Notch signaling also controls cell differentiation and tumorigenesis. However, the mechanisms through which Notch mediates microRNA expression are still unclear. In this study, we aimed to identi...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Niki, Masanori, Nakajima, Kohei, Ishikawa, Daichi, Nishida, Jun, Ishifune, Chieko, Tsukumo, Shin-ichi, Shimada, Mitsuo, Nagahiro, Shinji, Mitamura, Yoshinori, Yasutomo, Koji
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587792/
https://ncbi.nlm.nih.gov/pubmed/28878284
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10500-0
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