Somatic mutation profiles of clear cell endometrial tumors revealed by whole exome and targeted gene sequencing

BACKGROUND: The molecular pathogenesis of clear cell endometrial cancer (CCEC), a tumor type with a relatively unfavorable prognosis, is not well defined. We searched exome-wide for novel somatically mutated genes in CCECs, and assessed the mutational spectrum of known and candidate driver genes in...

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Pubblicato in:Cancer
Autori principali: Le Gallo, Matthieu, Rudd, Meghan L., Urick, Mary Ellen, Hansen, Nancy F., Zhang, Suiyuan, Lozy, Fred, Sgroi, Dennis C., Bel, August Vidal, Matias-Guiu, Xavier, Broaddus, Russell R., Lu, Karen H., Levine, Douglas A., Mutch, David G., Goodfellow, Paul J., Salvesen, Helga B., Mullikin, James C., Bell, Daphne W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5587124/
https://ncbi.nlm.nih.gov/pubmed/28485815
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cncr.30745
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