Transgenic overexpression of NanogP8 in the mouse prostate is insufficient to initiate tumorigenesis but weakly promotes tumor development in the Hi-Myc mouse model

This project was undertaken to address a critical cancer biology question: Is overexpression of the pluripotency molecule Nanog sufficient to initiate tumor development in a somatic tissue? Nanog1 is critical for the self-renewal and pluripotency of ES cells, and its retrotransposed homolog, NanogP8...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:Oncotarget
Main Authors: Liu, Bigang, Gong, Shuai, Li, Qiuhui, Chen, Xin, Moore, John, Suraneni, Mahipal V., Badeaux, Mark D., Jeter, Collene R., Shen, Jianjun, Mehmood, Rashid, Fan, Qingxia, Tang, Dean G.
פורמט: Artigo
שפה:Inglês
יצא לאור: Impact Journals LLC 2017
נושאים:
Research Paper
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC5581066/
https://ncbi.nlm.nih.gov/pubmed/28881767
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.17186
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