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Concise synthesis of (+)-fastigiatine
(+)-Fastigiatine was assembled in six steps from (R)-5-methylcyclohex-2-en-1-one. Intermolecular Diels–Alder reaction introduced most of the carbon atoms for the target. The two Boc-protected nitrogen atom building blocks were introduced by a Suzuki coupling and a cuprate addition. A biomimetic tran...
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| Pubblicato in: | Chem Sci |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Royal Society of Chemistry
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5580306/ https://ncbi.nlm.nih.gov/pubmed/28966768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c5sc03262h |
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