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Ultra-low dose of rituximab in rheumatoid arthritis: study protocol for a randomised controlled trial

BACKGROUND: A standard low-dosing schedule of rituximab (RTX; 2 × 500 mg or 1 × 1000 mg) is as effective for active rheumatoid arthritis (RA) as the registered dose (2 × 1000 mg). Moreover, several small uncontrolled studies suggest that even lower-dosed treatment with RTX also leads to good treatme...

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Détails bibliographiques
Publié dans:Trials
Auteurs principaux: den Broeder, Alfons A., Verhoef, Lise M., Fransen, Jaap, Thurlings, Rogier, van den Bemt, Bart J. F., Teerenstra, Steven, Boers, Nadine, den Broeder, Nathan, van den Hoogen, Frank H. J.
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577818/
https://ncbi.nlm.nih.gov/pubmed/28854956
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13063-017-2134-x
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