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Therapeutic effects of baicalein on rotenone-induced Parkinson’s disease through protecting mitochondrial function and biogenesis

Mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson’s disease (PD) for several decades, and disturbed mitochondrial biogenesis (mitobiogenesis) was recently found to be a common phenomenon in PD. Baicalein, a major bioactive flavone of Scutellaria baicalensis Georgi, exert...

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Enregistré dans:
Détails bibliographiques
Publié dans:Sci Rep
Auteurs principaux: Zhang, Xue, Du, Lida, Zhang, Wen, Yang, Yulin, Zhou, Qimeng, Du, Guanhua
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group UK 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577282/
https://ncbi.nlm.nih.gov/pubmed/28855526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07442-y
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