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Therapeutic effects of baicalein on rotenone-induced Parkinson’s disease through protecting mitochondrial function and biogenesis

Mitochondrial dysfunction has been implicated in the pathogenesis of Parkinson’s disease (PD) for several decades, and disturbed mitochondrial biogenesis (mitobiogenesis) was recently found to be a common phenomenon in PD. Baicalein, a major bioactive flavone of Scutellaria baicalensis Georgi, exert...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Zhang, Xue, Du, Lida, Zhang, Wen, Yang, Yulin, Zhou, Qimeng, Du, Guanhua
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5577282/
https://ncbi.nlm.nih.gov/pubmed/28855526
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-07442-y
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