Engineering of versatile redox partner fusions that support monooxygenase activity of functionally diverse cytochrome P450s

Most bacterial cytochrome P450 monooxygenases (P450s or CYPs) require two redox partner proteins for activity. To reduce complexity of the redox chain, the Bacillus subtilis flavodoxin YkuN (Y) was fused to the Escherichia coli flavodoxin reductase Fpr (R), and activity was tuned by placing flexible...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Bakkes, Patrick J., Riehm, Jan L., Sagadin, Tanja, Rühlmann, Ansgar, Schubert, Peter, Biemann, Stefan, Girhard, Marco, Hutter, Michael C., Bernhardt, Rita, Urlacher, Vlada B.
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2017
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5575160/
https://ncbi.nlm.nih.gov/pubmed/28852040
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-10075-w
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker