Enhancement of antitumor activity by using a fully human gene encoding a single-chain fragmented antibody specific for carcinoembryonic antigen

Human leukocyte antigen and/or costimulatory molecules are frequently lacking in metastatic tumor cells, and thus tumor cells are able to escape from the immune system. Although lymphocytes with a chimeric antigen receptor (CAR) is a promising approach for overcoming this challenge in cancer immunot...

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Bibliografiska uppgifter
I publikationen:Onco Targets Ther
Huvudupphovsmän: Shibaguchi, Hirotomo, Luo, Naixiang, Shirasu, Naoto, Kuroki, Motomu, Kuroki, Masahide
Materialtyp: Artigo
Språk:Inglês
Publicerad: Dove Medical Press 2017
Ämnen:
Original Research
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC5574594/
https://ncbi.nlm.nih.gov/pubmed/28860806
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/OTT.S140174
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