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Simultaneous rapid chemical synthesis of over one hundred oligonucleotides on a microscale

An inexpensive, extremely rapid manual method for simultaneous synthesis of large numbers of oligodeoxyribonucleotides on 50 or 150 nanomole scale is described. The oligonucleotides are assembled in parallel by the phosphotriester method on small cellulose paper disks in a simple gas pressure-contro...

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Detalhes bibliográficos
Main Authors: Matthes, Hans W.D., Zenke, W. Martin, Grundström, Thomas, Staub, Adrien, Wintzerith, Marguerite, Chambon, Pierre
Formato: Artigo
Idioma:Inglês
Publicado em: 1984
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC557430/
https://ncbi.nlm.nih.gov/pubmed/16453516
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