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The Role of O-GlcNAcylation in Perivascular Adipose Tissue Dysfunction of Offspring of High-Fat Diet-Fed Rats

Perivascular adipose tissue (PVAT), which reduces vascular contractility, is dysfunctional in the male offspring of rats fed a high-fat diet (HFD), partially due to a reduced NO bioavailability. O-GlcNAcylation of eNOS decreases its activity, thus we investigated the role of O-GlcNAcylation in the p...

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Détails bibliographiques
Publié dans:J Vasc Res
Auteurs principaux: Zaborska, Karolina E., Edwards, Gillian, Austin, Clare, Wareing, Mark
Format: Artigo
Langue:Inglês
Publié: S. Karger AG 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5569708/
https://ncbi.nlm.nih.gov/pubmed/28376507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1159/000458422
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