Systems biology approach to late-onset Alzheimer’s disease genome-wide association study identifies novel candidate genes validated using brain expression data and Caenorhabditis elegans experiments

INTRODUCTION: We sought to determine whether a systems biology approach may identify novel late-onset Alzheimer’s disease (LOAD) loci. METHODS: We performed gene-wide association analyses and integrated results with human protein-protein interaction data using network analyses. We performed function...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Alzheimers Dement
Main Authors: Mukherjee, Shubhabrata, Russell, Joshua C., Carr, Daniel T., Burgess, Jeremy D., Allen, Mariet, Serie, Daniel J., Boehme, Kevin L., Kauwe, John S. K., Naj, Adam C., Fardo, David W., Dickson, Dennis W., Montine, Thomas J., Ertekin-Taner, Nilufer, Kaeberlein, Matt R., Crane, Paul K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568992/
https://ncbi.nlm.nih.gov/pubmed/28242297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jalz.2017.01.016
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados