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Reduced levels of methyltransferase DNMT2 sensitize human fibroblasts to oxidative stress and DNA damage that is accompanied by changes in proliferation-related miRNA expression

Methyltransferase DNMT2 is suggested to be involved in the regulation of numerous processes, however its biological significance and underlying molecular mechanisms remain elusive. In the present study, we have used WI-38 and BJ human fibroblasts as an in vitro model system to investigate the effect...

詳細記述

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書誌詳細
出版年:Redox Biol
主要な著者: Lewinska, Anna, Adamczyk-Grochala, Jagoda, Kwasniewicz, Ewa, Deregowska, Anna, Semik, Ewelina, Zabek, Tomasz, Wnuk, Maciej
フォーマット: Artigo
言語:Inglês
出版事項: Elsevier 2017
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC5568885/
https://ncbi.nlm.nih.gov/pubmed/28843151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2017.08.012
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