Integration of the tricarboxylic acid (TCA) cycle with cAMP signaling and Sfl2 pathways in the regulation of CO(2) sensing and hyphal development in Candida albicans

Morphological transitions and metabolic regulation are critical for the human fungal pathogen Candida albicans to adapt to the changing host environment. In this study, we generated a library of central metabolic pathway mutants in the tricarboxylic acid (TCA) cycle, and investigated the functional...

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Veröffentlicht in:PLoS Genet
Hauptverfasser: Tao, Li, Zhang, Yulong, Fan, Shuru, Nobile, Clarissa J., Guan, Guobo, Huang, Guanghua
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567665/
https://ncbi.nlm.nih.gov/pubmed/28787458
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1006949
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