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Does Ceramide Form Channels? The Ceramide-Induced Membrane Permeabilization Mechanism

Ceramide is a sphingolipid involved in several cellular processes, including apoptosis. It has been proposed that ceramide forms large and stable channels in the mitochondrial outer membrane that induce cell death through direct release of cytochrome c. However, this mechanism is still debated becau...

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Foilsithe in:Biophys J
Main Authors: Artetxe, Ibai, Ugarte-Uribe, Begoña, Gil, David, Valle, Mikel, Alonso, Alicia, García-Sáez, Ana J., Goñi, Félix M.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The Biophysical Society 2017
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567600/
https://ncbi.nlm.nih.gov/pubmed/28834722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.071
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