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Does Ceramide Form Channels? The Ceramide-Induced Membrane Permeabilization Mechanism

Ceramide is a sphingolipid involved in several cellular processes, including apoptosis. It has been proposed that ceramide forms large and stable channels in the mitochondrial outer membrane that induce cell death through direct release of cytochrome c. However, this mechanism is still debated becau...

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Detalhes bibliográficos
Publicado no:Biophys J
Main Authors: Artetxe, Ibai, Ugarte-Uribe, Begoña, Gil, David, Valle, Mikel, Alonso, Alicia, García-Sáez, Ana J., Goñi, Félix M.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5567600/
https://ncbi.nlm.nih.gov/pubmed/28834722
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2017.06.071
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