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Activation of RhoA and ROCK Are Essential for Detachment of Migrating Leukocytes

Detachment of the rear of the cell from its substratum is an important aspect of locomotion. The signaling routes involved in this adhesive release are largely unknown. One of the few candidate proteins to play a role is RhoA, because activation of RhoA in many cell types leads to contraction, a mec...

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Autores principales: Alblas, Jacqueline, Ulfman, Laurien, Hordijk, Peter, Koenderman, Leo
Formato: Artigo
Lenguaje:Inglês
Publicado: The American Society for Cell Biology 2001
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC55668/
https://ncbi.nlm.nih.gov/pubmed/11452009
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