EMT-like circulating tumor cells in ovarian cancer patients are enriched by platinum-based chemotherapy

BACKGROUND: Assuming that tumor cell dissemination requires a shift to a mesenchymal phenotype, we analyzed the incidence of epithelial-to-mesenchymal-transition (EMT)-like circulating tumor cells (CTCs) in ovarian cancer patients and inquired, how their molecular phenotypes respond to platinum-base...

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Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Chebouti, Issam, Kasimir-Bauer, Sabine, Buderath, Paul, Wimberger, Pauline, Hauch, Siegfried, Kimmig, Rainer, Kuhlmann, Jan Dominik
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564727/
https://ncbi.nlm.nih.gov/pubmed/28415744
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.16179
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