Non-invasive detection of somatic mutations using next-generation sequencing in primary central nervous system lymphoma

PURPOSE: Primary central nervous system lymphomas (PCNSL) have recurrent genomic alterations. The main objective of our study was to demonstrate that targeted sequencing of circulating cell-free DNA (cfDNA) released by PCNSL at the time of diagnosis could identify somatic mutations by next-generatio...

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Published in:Oncotarget
Main Authors: Fontanilles, Maxime, Marguet, Florent, Bohers, Élodie, Viailly, Pierre-Julien, Dubois, Sydney, Bertrand, Philippe, Camus, Vincent, Mareschal, Sylvain, Ruminy, Philippe, Maingonnat, Catherine, Lepretre, Stéphane, Veresezan, Elena-Liana, Derrey, Stéphane, Tilly, Hervé, Picquenot, Jean-Michel, Laquerrière, Annie, Jardin, Fabrice
Format: Artigo
Language:Inglês
Published: Impact Journals LLC 2017
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Research Paper
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5564634/
https://ncbi.nlm.nih.gov/pubmed/28636991
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.18325
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