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In silico analysis of glycinamide ribonucleotide transformylase inhibition by PY873, PY899 and DIA
In humans, purine de novo synthesis pathway consists of multi-functional enzymes. Nucleotide metabolism enzymes are potential drug targets for treating cancer and autoimmune diseases. Glycinamide ribonucleotide transformylase (GART) is one of the most important trifunctional enzymes involved in puri...
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| Publicado no: | Saudi J Biol Sci |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Elsevier
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5562383/ https://ncbi.nlm.nih.gov/pubmed/28855807 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.sjbs.2014.11.008 |
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