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Delivery of a drug cache to glioma cells overexpressing platelet-derived growth factor receptor using lipid nanocarriers

AIM: Glioblastoma multiforme is a devastating disease with no curative options due to the difficulty in achieving sufficient quantities of effective chemotherapies into the tumor past the blood–brain barrier. Micelles loaded with temozolomide (TMZ) were designed to increase the delivery of this drug...

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Publicado en:Nanomedicine (Lond)
Autores principales: Miller, Kayla, Dixit, Suraj, Bredlau, Amy-Lee, Moore, Alfred, McKinnon, Emilie, Broome, Ann-Marie
Formato: Artigo
Lenguaje:Inglês
Publicado: Future Medicine Ltd 2016
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5561905/
https://ncbi.nlm.nih.gov/pubmed/27003178
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/nnm.15.218
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