Prolonged Pemetrexed Infusion Plus Gemcitabine in Refractory Metastatic Colorectal Cancer: Preclinical Rationale and Phase II Study Results

LESSONS LEARNED. Difficulties in translating in vitro results into clinical practice are inevitable. Further efforts to verify the efficacy of alternative schedules of pemetrexed in solid tumors are encouraged. BACKGROUND. We investigated the cytotoxic activity of pemetrexed in combination with seve...

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Detalhes bibliográficos
Publicado no:Oncologist
Main Authors: Passardi, Alessandro, Fanini, Francesca, Turci, Livia, Foca, Flavia, Rosetti, Paola, Ruscelli, Silvia, Casadei Gardini, Andrea, Valgiusti, Martina, Dazzi, Claudio, Marangolo, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: AlphaMed Press 2017
Assuntos:
Clinical Trial Results
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553965/
https://ncbi.nlm.nih.gov/pubmed/28592624
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1634/theoncologist.2017-0206
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