PAR-TERRA directs homologous sex chromosome pairing

In mammals, homologous chromosomes rarely pair outside of meiosis. An exception is the X-chromosome, which transiently pairs during X-chromosome inactivation (XCI). How two chromosomes find each other in 3D space is not known. Here, we reveal a required interaction between the X-inactivation center...

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Udgivet i:Nat Struct Mol Biol
Main Authors: Chu, Hsueh-Ping, Froberg, John E., Kesner, Barry, Oh, Hyun Jung, Ji, Fei, Sadreyev, Ruslan, Pinter, Stefan F., Lee, Jeannie T.
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5553554/
https://ncbi.nlm.nih.gov/pubmed/28692038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.3432
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