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A novel method to demonstrate that pregnant women with polycystic ovary syndrome hyper-expose their fetus to androgens as a possible stepping stone for the developmental theory of PCOS. A pilot study

BACKGROUND: Polycystic ovary syndrome (PCOS), whose aetiology is unknown, is predominately a familial syndrome but confirmation of candidate genes has proved elusive. The developmental hypothesis for the origin of PCOS suggests that exposure of the fetus to excess androgens influences imprinting, le...

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Détails bibliographiques
Publié dans:Reprod Biol Endocrinol
Auteurs principaux: Homburg, Roy, Gudi, Anil, Shah, Amit, M. Layton, Alison
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5549310/
https://ncbi.nlm.nih.gov/pubmed/28789693
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12958-017-0282-1
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