Mutations targeting the coagulation pathway are enriched in brain metastases

Brain metastases (BMs) are the most common malignancy of the central nervous system. Recently it has been demonstrated that plasminogen activator inhibitor serpins promote brain metastatic colonization, suggesting that mutations in serpins or other members of the coagulation cascade can provide crit...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Richichi, Cristina, Fornasari, Lorenzo, Melloni, Giorgio E. M., Brescia, Paola, Patanè, Monica, Del Bene, Massimiliano, Mustafa, Dana A. M., Kros, Johan M., Pollo, Bianca, Pruneri, Giancarlo, Sciandivasci, Angela, Munzone, Elisabetta, DiMeco, Francesco, Pelicci, Pier Giuseppe, Riva, Laura, Pelicci, Giuliana
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5529435/
https://ncbi.nlm.nih.gov/pubmed/28747664
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06811-x
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