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Challenges and progress in interpretation of non-coding genetic variants associated with human disease
Genome-wide association studies have shown that the far majority of disease-associated variants reside in the non-coding regions of the genome, suggesting that gene regulatory changes contribute to disease risk. To identify truly causal non-coding variants and their affected target genes remains cha...
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| Publié dans: | Exp Biol Med (Maywood) |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
SAGE Publications
2017
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5529005/ https://ncbi.nlm.nih.gov/pubmed/28581336 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1535370217713750 |
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