Combination of novel HER2‐targeting antibody 1E11 with trastuzumab shows synergistic antitumor activity in HER2‐positive gastric cancer

The synergistic interaction of two antibodies targeting the same protein could be developed as an effective anti‐cancer therapy. Human epidermal growth factor receptor 2 (HER2) is overexpressed in 20–25% of breast and gastric cancer patients, and HER2‐targeted antibody therapy using trastuzumab is e...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Ko, Bong-Kook, Lee, Sook-Yeon, Lee, Young-Ha, Hwang, In-Sik, Persson, Helena, Rockberg, Johan, Borrebaeck, Carl, Park, Dongeun, Kim, Kyu-Tae, Uhlen, Mathias, Lee, Jong-Seo
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2014
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Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5528653/
https://ncbi.nlm.nih.gov/pubmed/25306393
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2014.09.007
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