Autophagy in tumour suppression and promotion

Autophagy, a well‐described cellular mechanism for lysosomal degradation of cytoplasmic content, has emerged as a tumour suppression pathway. Recent evidence indicates that the tumour suppressor function of autophagy is mediated by scavenging of damaged oxidative organelles, thereby preventing accum...

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Bibliographic Details
Published in:Mol Oncol
Main Authors: Brech, Andreas, Ahlquist, Terje, Lothe, Ragnhild A., Stenmark, Harald
Format: Artigo
Language:Inglês
Published: John Wiley and Sons Inc. 2009
Subjects:
Reviews
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527946/
https://ncbi.nlm.nih.gov/pubmed/19559660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molonc.2009.05.007
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