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Pharmacokinetics of Pyrazinamide and Optimal Dosing Regimens for Drug-Sensitive and -Resistant Tuberculosis

Pyrazinamide is used in the treatment of tuberculosis (TB) because its sterilizing effect against tubercle bacilli allows the shortening of treatment. It is part of standard treatment for drug-susceptible and drug-resistant TB, and it is being considered as a companion drug in novel regimens. The ai...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Antimicrob Agents Chemother
Hauptverfasser: Chirehwa, Maxwell T., McIlleron, Helen, Rustomjee, Roxana, Mthiyane, Thuli, Onyebujoh, Philip, Smith, Peter, Denti, Paolo
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5527644/
https://ncbi.nlm.nih.gov/pubmed/28607022
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00490-17
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