Epigallocatechin-3-gallate (EGCG) consumption in the Ts65Dn model of Down syndrome fails to improve behavioral deficits and is detrimental to skeletal phenotypes

Down syndrome (DS) is caused by three copies of human chromosome 21 (Hsa21) and results in phenotypes including intellectual disability and skeletal deficits. Ts65Dn mice have three copies of ~50% of the genes homologous to Hsa21 and display phenotypes associated with DS, including cognitive deficit...

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Detalhes bibliográficos
Publicado no:Physiol Behav
Main Authors: Stringer, Megan, Abeysekera, Irushi, Thomas, Jared, LaCombe, Jonathan, Stancombe, Kailey, Stewart, Robert J., Dria, Karl J., Wallace, Joseph M., Goodlett, Charles R., Roper, Randall J.
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525541/
https://ncbi.nlm.nih.gov/pubmed/28478033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.physbeh.2017.05.003
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