Mesenchymal Stromal Cells Accelerate Epithelial Tight Junction Assembly via the AMP-Activated Protein Kinase Pathway, Independently of Liver Kinase B1

BACKGROUND: Mesenchymal stromal cells (MSC) are fibroblast-like multipotent cells capable of tissue-repair properties. Given the essentiality of tight junctions (TJ) in epithelial integrity, we hypothesized that MSC modulate TJ formation, via the AMP-activated kinase (AMPK) pathway. Liver kinase-β1...

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Udgivet i:Stem Cells Int
Main Authors: Rowart, P., Erpicum, P., Krzesinski, J.-M., Sebbagh, M., Jouret, F.
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5525096/
https://ncbi.nlm.nih.gov/pubmed/28781597
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2017/9717353
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