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In vivo assessment of intracellular redox-state in rat liver using hyperpolarized [1-(13)C]alanine
PURPOSE: The intracellular lactate to pyruvate concentration ratio is a commonly used tissue assay biomarker of redox, being proportional to free cytosolic [NADH]/[NAD(+)]. In this work, we assess the utility of hyperpolarized [1-(13)C]alanine, and the subsequent detection of the intracellular produ...
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| Publicado no: | Magn Reson Med |
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| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5523144/ https://ncbi.nlm.nih.gov/pubmed/28261868 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/mrm.26662 |
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