Recombinant human protein C derivatives: altered response to calcium resulting in enhanced activation by thrombin.

Calcium plays a dual role in the activation of protein C: it inhibits protein C activation by alpha-thrombin, whereas it is required for protein C activation by the thrombomodulin-thrombin complex. Available information suggests that these calcium effects are mediated through calcium induced structu...

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Bibliographic Details
Main Authors: Ehrlich, H J, Grinnell, B W, Jaskunas, S R, Esmon, C T, Yan, S B, Bang, N U
Format: Artigo
Language:Inglês
Published: 1990
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC552260/
https://ncbi.nlm.nih.gov/pubmed/2369894
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