Human intrahepatic CD69 + CD8+ T cells have a tissue resident memory T cell phenotype with reduced cytolytic capacity

Tissue resident memory T cells (T(RM)) have been identified in various tissues, however human liver T(RM) to date remain unidentified. T(RM) can be recognized by CD69 and/or CD103 expression and may play a role in the pathology of chronic hepatitis B (CHB) and hepatitis C virus infection (CHC). Live...

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Publicado no:Sci Rep
Main Authors: Stelma, Femke, de Niet, Annikki, Sinnige, Marjan J., van Dort, Karel A., van Gisbergen, Klaas P. J. M., Verheij, Joanne, van Leeuwen, Ester M. M., Kootstra, Neeltje A., Reesink, Hendrik W.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522381/
https://ncbi.nlm.nih.gov/pubmed/28733665
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-06352-3
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