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Role of microRNA-130b in placental PGC-1α/TFAM mitochondrial biogenesis pathway

Diabetes during pregnancy is associated with abnormal placenta mitochondrial function and increased oxidative stress, which affect fetal development and offspring long-term health. Peroxisome proliferator-activated receptor-γ coactivator-1α (PGC-1α) is a master regulator of mitochondrial biogenesis...

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Détails bibliographiques
Publié dans:Biochem Biophys Res Commun
Auteurs principaux: Jiang, Shaoning, Teague, April M., Tryggestad, Jeanie B., Chernausek, Steven D.
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5522006/
https://ncbi.nlm.nih.gov/pubmed/28433632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbrc.2017.04.099
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