Potentiating the effects of radiotherapy in rectal cancer: the role of aspirin, statins and metformin as adjuncts to therapy

BACKGROUND: Complete tumour response (pCR) to neo-adjuvant chemo-radiotherapy for rectal cancer is associated with a reduction in local recurrence and improved disease-free and overall survival, but is achieved in only 20–30% of patients. Drug repurposing for anti-cancer treatments is gaining moment...

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Bibliografische gegevens
Gepubliceerd in:Br J Cancer
Hoofdauteurs: Gash, K J, Chambers, A C, Cotton, D E, Williams, A C, Thomas, M G
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group 2017
Onderwerpen:
Translational Therapeutics
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520519/
https://ncbi.nlm.nih.gov/pubmed/28641310
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.175
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