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SPATA2: more than a missing link

The assembly of the TNFR1 signalling complex (TNF-RSC) depends on K63- and M1-linked ubiquitylation, promoting the recruitment of complex constituents and the stability of the complex. Ubiquitylation is a dynamic process, controlled by E3 ubiquitin ligases as well as deubiquitinases, such as CYLD an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Death Differ
Prif Awduron: Schlicher, Lisa, Brauns-Schubert, Prisca, Schubert, Florian, Maurer, Ulrich
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2017
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5520165/
https://ncbi.nlm.nih.gov/pubmed/28282038
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cdd.2017.26
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