Mucin 2 silencing promotes colon cancer metastasis through interleukin-6 signaling

Downregulation of Mucin 2 (MUC2) expression is associated with early carcinogenesis events in colon cancer. MUC2 plays a role in the progression of colon cancer, and reduced MUC2 protein expression correlates with increased interleukin-6 (IL-6) expression. However, the interaction between MUC2 and I...

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Published in:Sci Rep
Main Authors: Hsu, Hui-Ping, Lai, Ming-Derg, Lee, Jenq-Chang, Yen, Meng-Chi, Weng, Tzu-Yang, Chen, Wei-Ching, Fang, Jung-Hua, Chen, Yi-Ling
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517441/
https://ncbi.nlm.nih.gov/pubmed/28725043
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-017-04952-7
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