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Directed migration of cancer cells by the graded texture of the underlying matrix

Living cells and the extracellular matrix (ECM) can display complex interactions that define key developmental, physiological and pathological processes. Here, we report a new type of directed migration — which we term ‘topotaxis’ — by which cell movement is guided by the gradient of the nanoscale t...

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Dettagli Bibliografici
Pubblicato in:Nat Mater
Autori principali: Park, JinSeok, Kim, Deok-Ho, Kim, Hong-Nam, Wang, Chiaochun Joanne, Kwak, Moon Kyu, Hur, Eunmi, Suh, Kahp-Yang, An, Steven S., Levchenko, Andre
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517090/
https://ncbi.nlm.nih.gov/pubmed/26974411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4586
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