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Directed migration of cancer cells by the graded texture of the underlying matrix
Living cells and the extracellular matrix (ECM) can display complex interactions that define key developmental, physiological and pathological processes. Here, we report a new type of directed migration — which we term ‘topotaxis’ — by which cell movement is guided by the gradient of the nanoscale t...
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Published in: | Nat Mater |
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Main Authors: | , , , , , , , , |
Format: | Artigo |
Language: | Inglês |
Published: |
2016
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Subjects: | |
Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5517090/ https://ncbi.nlm.nih.gov/pubmed/26974411 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4586 |
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