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Directed migration of cancer cells by the graded texture of the underlying matrix

Living cells and the extracellular matrix (ECM) can display complex interactions that define key developmental, physiological and pathological processes. Here, we report a new type of directed migration — which we term ‘topotaxis’ — by which cell movement is guided by the gradient of the nanoscale t...

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Bibliographic Details
Published in:Nat Mater
Main Authors: Park, JinSeok, Kim, Deok-Ho, Kim, Hong-Nam, Wang, Chiaochun Joanne, Kwak, Moon Kyu, Hur, Eunmi, Suh, Kahp-Yang, An, Steven S., Levchenko, Andre
Format: Artigo
Language:Inglês
Published: 2016
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC5517090/
https://ncbi.nlm.nih.gov/pubmed/26974411
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmat4586
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