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Harnessing selenocysteine reactivity for oxidative protein folding
Although oxidative folding of disulfide-rich proteins is often sluggish, this process can be significantly enhanced by targeted replacement of cysteines with selenocysteines. In this study, we examined the effects of a selenosulfide and native versus nonnative diselenides on the folding rates and me...
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| Udgivet i: | Chem Sci |
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| Main Authors: | , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Royal Society of Chemistry
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5514408/ https://ncbi.nlm.nih.gov/pubmed/28757941 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c4sc02379j |
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