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Heparan Sulfate Proteoglycan Is an Important Attachment Factor for Cell Entry of Akabane and Schmallenberg Viruses

Akabane virus (AKAV) and Schmallenberg virus (SBV) are members of the genus Orthobunyavirus, which are transmitted by arthropod vectors with a broad cellular tropism in vitro as well as in vivo. Both AKAV and SBV cause arthrogryposis-hydranencephaly syndrome in ruminants. The main cellular receptor...

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Publicado en:J Virol
Autores principales: Murakami, Shin, Takenaka-Uema, Akiko, Kobayashi, Tomoya, Kato, Kentaro, Shimojima, Masayuki, Palmarini, Massimo, Horimoto, Taisuke
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5512253/
https://ncbi.nlm.nih.gov/pubmed/28539443
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00503-17
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