Differential effects of early-life nutrient restriction in long-lived GHR-KO and normal mice

There is increasing evidence that growth hormone (GH) and insulin-like growth factor 1 (IGF-1) signaling (collectively referred to as somatotropic signaling) during development has a profound influence on aging and longevity. Moreover, the absence of GH action was shown to modify responses of adult...

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Publicado en:GeroScience
Autores principales: Fang, Yimin, McFadden, Samuel, Darcy, Justin, Hill, Cristal M., Huber, Joshua A., Verhulst, Steve, Kopchick, John J., Miller, Richard A., Sun, Liou Y., Bartke, Andrzej
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer International Publishing 2017
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Original Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5505892/
https://ncbi.nlm.nih.gov/pubmed/28523599
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-017-9978-6
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