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Exploring the Impact of Cleavage and Polyadenylation Factors on Pre-mRNA Splicing Across Eukaryotes
In human, mouse, and Drosophila, the spliceosomal complex U1 snRNP (U1) protects transcripts from premature cleavage and polyadenylation at proximal intronic polyadenylation signals (PAS). These U1-mediated effects preserve transcription integrity, and are known as telescripting. The watchtower role...
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| Published in: | G3 (Bethesda) |
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| Main Authors: | , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
Genetics Society of America
2017
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5499120/ https://ncbi.nlm.nih.gov/pubmed/28500052 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.117.041483 |
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