Network Reconstruction Reveals that Valproic Acid Activates Neurogenic Transcriptional Programs in Adult Brain Following Traumatic Injury

OBJECTIVES: To determine the mechanism of action of valproic acid (VPA) in the adult central nervous system (CNS) following traumatic brain injury (TBI) and hemorrhagic shock (HS). METHODS: Data were analyzed from different sources, including experiments in a porcine model, data from postmortem huma...

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Detalhes bibliográficos
Publicado no:Pharm Res
Main Authors: Higgins, Gerald A., Georgoff, Patrick, Nikolian, Vahagn, Allyn-Feuer, Ari, Pauls, Brian, Higgins, Richard, Athey, Brian D., Alam, Hasan E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer US 2017
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5498621/
https://ncbi.nlm.nih.gov/pubmed/28271248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11095-017-2130-6
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