Gene Transfer Agent Promotes Evolvability within the Fittest Subpopulation of a Bacterial Pathogen

The Bartonella gene transfer agent (BaGTA) is an archetypical example for domestication of a phage-derived element to permit high-frequency genetic exchange in bacterial populations. Here we used multiplexed transposon sequencing (TnSeq) and single-cell reporters to globally define the core componen...

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發表在:Cell Syst
Main Authors: Québatte, Maxime, Christen, Matthias, Harms, Alexander, Körner, Jonas, Christen, Beat, Dehio, Christoph
格式: Artigo
語言:Inglês
出版: Cell Press 2017
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496983/
https://ncbi.nlm.nih.gov/pubmed/28624614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cels.2017.05.011
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