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Identity-by-descent refines mapping of candidate regions for preaxial polydactyly II /III in a large Chinese pedigree

Preaxial polydactyly (PPD) is congenital hand malformation characterized by the duplication of digit. Herein, we scan the genome-wide SNPs for a large Chinese family with PPD-II/III. We employ the refined IBD algorithm to identify the identity-by-decent (IBD) segments and compare the frequency among...

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Detalhes bibliográficos
Publicado no:Hereditas
Main Authors: Yang, Xingyan, Shen, Quankuan, Sulaiman, Xierzhatijiang, Liu, Hequn, Peng, Minsheng, Zhang, Yaping
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5496229/
https://ncbi.nlm.nih.gov/pubmed/28690477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s41065-017-0040-6
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